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Structure of the MECP2 gene and mRNA (adapted from Kriaucionis and Bird,30 and Mnatzakanian et al31). Alternative splicing for the A ( isoform is shown above the gene and for the B ( isoform below the gene. The B isoform has the highest expression in brain, and mutations specific to this isoform are sufficient to cause RS.31 (B) Structure of the B isoform MeCP2 protein sequence.
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Backpack and mobile phone: Each CHW is given a mobile smartphone costing US$ 150, a solar charger costing US$ 40 and a data plan costing US$ 480 per year for supervisory support, communication and data collection. To reduce costs, national CHW programmes can establish closed user groups a nationwide network that allows free calls and short message service between identified health staff. Each CHW is also given a backpack costing US$ 10 to carry supplies..
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